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Thursday, March 26, 2020

Database of the New Corona Virus- Covid19

Corona viruses (Cov) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). The new Corona virus disease (COVID-19) was first reported from Wuhan, The first case of someone in China suffering from COVID-19 can be traced back to November 17.On December 27, Zhang Jixian, a doctor from Hubei Provincial Hospital of Integrated Chinese and Western Medicine, told China's health authorities that the disease was caused by a new coronavirus..The first case of the 2019–20 coronavirus pandemic in India was reported on 30 January 2020,

Common signs of infection include fever, cough, myalgia, fatigue and breathing difficulties. In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death. The function of the immune system is critical in the human response to infectious disease. Viral infections induce oxidative stress and cause damage to airway epithelial cells. A growing body of evidence identifies stress, nutrition and immunity as a cofactor in infectious disease susceptibility and outcomes. The mainstay in management of

corona viral infections has been supportive care, nutrition and preventing further progression in the absence of any antiviral agent or vaccine.

During Ebola outbreak in 2014 expert group of WHO has recommended that "it is ethical to offer unproven interventions with as yet unknown efficacy and adverse effects, as potential treatment or prevention" keeping in view no vaccine or anti-virals were available.

As per the central council of research in homoeopathy , India, CCRH As prophylaxis and a immune booster ,Arsenicum album 30, daily once in empty stomach for three days. The dose should be repeated after one month by following the same schedule till Corona virus infections prevalent in the community. In one of the studies Arsenic album as one of the constituents in a formulation affected HT29 cells and human macrophages. Also, it showed .j.NF-KB hyperactivity (reduced expression of reporter gene GFP in transfected HT29 cells), .J,TNF-a release in macrophages. More over Arsenic album is a common prescription in the cases of respiratory infections in day to day practice.

Varous links have been collected to help the researchers and the medical fraternity 

India Data Update can be seen below

World Data can be seen here

More data on covid19

Public Datasets for Research & Innovation on Coronavirus- World wide
1. COVID-19 Open Research Dataset (CORD-19) - 29,000 articles on Coronavirus for text mining: https://pages.semanticscholar.org/coronavirus-research

2. COVID-19 Epidemiological Data Repository by Johns Hopkins University Center for Systems Science & Engineering (JHU
CCSE): https://github.com/CSSEGISandData/COVID-19

3. European Center for Disease Control & Prevention (ECDC) - COVID-19 Epidemiological Data:https://www.ecdc.europa.eu/en/publications-data/download-todays-data-geographic-distribution-covid-19-cases-worldwide

4. U.S. Hospital Capacity Estimates (Harvard Global Health Institute): https://globalepidemics.org/2020/03/17/caring-for-covid-19-patients/

5. U.S. State COVID-19 Testing Data:https://covidtracking.com/

6. Italy COVID-19 Data: https://github.com/pcm-dpc/COVID-19

7. WHO COVID-19 Data - Cases & Deaths in China (by province) and other countries:https://data.humdata.org/dataset/coronavirus-covid-19-cases-data-for-china-and-the-rest-of-the-world

8. ACAPS COVID-19: Government Measures Dataset: https://data.humdata.org/dataset/acaps-covid19-government-measures-dataset

9. World Bank Indicators (population health & healthcare systems) relevant to COVID-19: https://data.humdata.org/dataset/world-bank-indicators-of-interest-to-the-covid-19-outbreak

10. GeneBank COVID-19 Genetic Sequences: https://www.ncbi.nlm.nih.gov/genbank/sars-cov-2-seqs/

11. Next Strain - COVID-19 Genomics Database: https://nextstrain.org/ncov


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